—   Motor symptoms: tremor, slow movements, stiffness ...

—   Non-motor symptoms: constipation, possible dementia ...

—   Dopamine shortage ← misfolded alpha-synuclein(?) ← ?

—   Prevalence: 127,000 PwP (people with Parkinson's) in UK:
40-45, under 1/10000
60-65, 23/10000
80-85, 170/10000

—   Drugs (levodopa) make a big difference for 10-20 years.